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Artesunate-induced anaemia: A case report of a pharmacological complication to consider.
Parasitol Int
January 2025
Infectious Diseases Division, Fundación Jiménez Díaz University Hospital, Madrid, Spain.
Article Synopsis
- A 52-year-old man was admitted to the ICU in septic shock from severe malaria after traveling to Ghana, with a high parasitaemia index of 50%.
- He was treated with intravenous artesunate and dihydroartemisinin plus piperaquine, leading to rapid clinical improvement and a 0% parasitaemia level within 72 hours, but developed severe anaemia with hemoglobin dropping to 5.6 g/dL.
- The anaemia was diagnosed as post-artesunate haemolytic anaemia (PDAH) due to high parasitaemia and treatment, treated with oral steroids, highlighting the need for awareness of PDAH in severe malaria cases for effective recovery.
Solid-phase red cell adherence versus gel column agglutination: Is there any difference for the detection of alloantibodies associated with the JK system?
Transfusion
January 2025
Blood Bank - Laboratory of Immunohematology, Centre Hospitalier Universitaire Brugmann/Université Libre de Bruxelles (ULB), Brussels, Belgium.
Background: Detection of alloantibodies associated with the JK system may be tricky. They are nevertheless associated with transfusion reactions and their detection is crucial.
Study Design And Methods: Retrospectively and over a period of 7 years, we compared the results obtained using two different assays for antibody detection.
An Unusual Case of Overlapping Immunoglobulin G4-Related Disease and Systemic Lupus Erythematosus.
Cureus
December 2024
Nephrology, Unidade Local de Saúde de São José, Lisbon, PRT.
Immunoglobulin G4-related disease (IgG4-RD) and systemic lupus erythematosus (SLE) are multisystemic autoimmune disorders that can present with renal manifestations. Overlapping cases of these diseases are extremely rare and present both diagnostic and therapeutic challenges. We report the case of a 70-year-old male with a history of autoimmune pancreatitis, who was admitted with fatigue, weight loss, and worsening kidney function.
View Article and Find Full Text PDFDevelopment and Validation of Emoji Response Scales for Assessing Patient-Reported Outcomes.
JCO Clin Cancer Inform
January 2025
Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, AZ.
Purpose: Emoji are digital images or icons used to express an idea or emotion in electronic communication. The purpose of this study was to develop and evaluate the psychometric properties of two patient-reported scales that incorporate emoji.
Methods: The Emoji Response Scale developed for this study has two parts: the Emoji-Ordinal and Emoji-Mood scales.
Severe mycoplasma pneumoniae pneumonia combined with cold agglutinin disease and pulmonary embolism in childhood: A case report and review of the literature.
Afr J Reprod Health
November 2024
Department of Pediatrics, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai 264000, Shandong, China.
This was a case report and literature review, aimed to strengthen the understanding and therapy of mycoplasma pneumoniae (MP) pneumonia combined with cold agglutinin disease and pulmonary embolism in children. A 7-year-old boy was taken to the hospital with fever for 7 days, cough for 5 days, and recurrent cyanosis at the extremities of one day duration. Pulmonary artery computed tomography angiography (CTA) showed pulmonary embolism, double pneumonia, and pleural effusion.
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