AI Article Synopsis

  • The study tracked patients receiving low-dose CDDP+5-FU chemotherapy through hepatic arterial infusion for colorectal cancer liver metastases in an outpatient setting.
  • Two patients achieved complete response (CR) and seven had partial response (PR), although two of the responders later developed lung metastases.
  • The findings suggest that while this treatment can be effective, managing metastases outside the liver is crucial for extending patient survival.

Article Abstract

We followed patients who underwent hepatic arterial infusion chemotherapy with low-dose CDDP+5-FU for liver metastases from colorectal cancer in the outpatient setting. A catheter was inserted from the femoral artery into the proper hepatic artery using the interventional technique. Two complete response (CR) and seven partial response (PR) were achieved, but later 2 of these patients had lung metastases. We conclude that this therapy may be effective, but control of extrahepatic lesions is necessary for life prolongation.

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