[An 8-year study of depression effects on myocardial infarction risk in a population of 25-64 year old men].

Aim: To study depression effects on the risk of myocardial infarction (MI) for 8 years in men aged 25-64 years.

Material And Methods: A random representative sample of men (n = 657) at the age between 25 and 64 living in Novosibirsk were screened in 1994 in the scope of WHO program "MONICA-psychosocial". The response was 82.1%. WHO "Register of Acute Myocardial Infarction" detected 58 cases of MI in the control period 1994-2002. Statistics were obtained with the program set SPSS-10. Cox regression model was used for estimation of a relative MI risk (RMIR).

Results: RMIR in 25-64-year-old men for 8 years was 2-fold higher in men with depression than without it, in the age group of 55-64-old men--5-fold. Depression was in 65.8% MI patients. The highest RMIR was in men with depression engaged in hard labour, retired, poorly educated, divorced, widowed.

Conclusion: Risk of MI in men is related to depression due to social and economic status.