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A comparative approach on the prophylactic impact of fermented beverages on acute ulcerative colitis in mouse model.
Pol J Vet Sci
December 2024
Department of Pathology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, 15030, İstiklal Campus, Burdur, Turkey.
Acute ulcerative colitis is an inflammatory disease of the colon that is becoming increasingly prevalent. Yet, a growing body of evidence supports the efficacy of dietary interventions in preventing acute ulcerative colitis. Fermented beverages have been the focus of research in humans and animals for several years due to their potential to influence overall health functions with an emphasis on gut health.
View Article and Find Full Text PDFUlcer in a Bulbar Diverticulum: An Atypical Localization and Rare Complication of Gastrointestinal Hemorrhage.
Cureus
November 2024
Gastroenterology, Groupe Hospitalier de la Haute Saone, Vesoul, FRA.
Gastrointestinal bleeding remains a frequent reason for emergency consultations, with a mortality rate that is still worrying despite advances in treatment. The most common cause is gastro-duodenal ulcers, mainly linked to Helicobacter pylori. Unusual causes such as gastroduodenal diverticular haemorrhage, a rare and serious complication, can also be detected during endoscopy.
View Article and Find Full Text PDFProtective Role of Selenium-Binding Protein 1 (SELENBP1) in Patients with Ulcerative Colitis.
Metabolites
December 2024
Inflammatory Bowel Disease Clinic, Department of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico City 14080, CP, Mexico.
Background: The expression of selenium-binding protein 1 (SELENBP1), a molecule responsible for the absorption of selenium in the colon, is crucial for its immunoregulatory effect, but this phenomenon has not been studied in patients with UC. The present study aimed to determine the clinical outcome of SELENBP1 expression in colonic tissue from patients with UC.
Methods: The relative mRNA expression of SELENBP1 was analyzed in 34 patients with UC and 20 controls.
Lithium Coupled with C6-Carboxyl Improves the Efficacy of Oligoguluronate in DSS-Induced Ulcerative Colitis in C57BL/6J Mice.
Mar Drugs
December 2024
Key Laboratory of Marine Drugs of Ministry of Education, Shandong Key Laboratory of Glycoscience and Glycotechnology, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Oligoguluronate lithium (OGLi) was prepared for the purpose of enhancing the anti-ulcerative colitis (UC) activities of OG, in which lithium (Li) is coupled with the C6-carboxyl of G residue. The therapeutic effects of OGLi on dextran sulfate (DSS)-induced UC mice were investigated, and oligoguluronate sodium (OGNa) and lithium carbonate (LC) were used as contrasts. The effects of OGLi, OGNa and LC on the treatment of UC mice were studied by monitoring body weight change and evaluating colon length, the disease activity index (DAI), histopathological examination and gut microbiota regulation.
View Article and Find Full Text PDFKey Risk Factors, Sex Differences, and the Influence of High-Intensity Exercise on Colorectal Carcinogenesis: A 10-Year Cohort Study Based on 1,120,377 Individuals from the NHISS Data.
Curr Oncol
November 2024
School of Kinesiology, Yeungnam University, 280, Daehak-ro, Gyeongsan 38541, Gyeongbuk, Republic of Korea.
Colorectal cancer (CRC) is the third most common cancer globally. Therefore, this study aims to examine data from the National Health Insurance Sharing Service (NHISS) to investigate factors influencing colon cancer incidence, focusing on key variables and optimal cutoff points. The patient cohort from the NHISS database included 1,120,377 individuals aged 1-85 years.
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