In the monkey brain, two interconnected cortical areas have distinctive neuronal responses to visual, tactile, and auditory stimuli. These areas are the ventral intraparietal area (VIP) and a polysensory zone in the precentral gyrus (PZ). The multimodal neurons in these areas typically respond to objects touching, near, or looming toward the body surface. Electrical stimulation of these areas evokes defensive-like withdrawing or blocking movements. These areas have been suggested to participate in a range of functions including navigation by optic flow, attention to nearby space, and the processing of object location for the guidance of movement. We suggest that a major emphasis of these areas is the construction of a margin of safety around the body and the selection and coordination of defensive behavior. In this review, we summarize the physiological properties of these brain areas and discuss a range of behavioral phenomena that might be served by those neuronal properties, including the ducking and blocking reactions that follow startle, the flight zone of animals, the personal space of humans, the nearby, multimodal attentional space that has been studied in humans, the withdrawal reaction to looming visual stimuli, and the avoidance of obstacles during self-motion such as locomotion or reaching.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.neuropsychologia.2005.09.009 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Generalized measures of population synchrony.
Math Biosci
December 2024
Department of Biology, Duke University, Durham, NC, USA.
Synchronized behavior among individuals, broadly defined, is a ubiquitous feature of populations. Understanding mechanisms of (de)synchronization demands meaningful, interpretable, computable quantifications of synchrony, relevant to measurements that can be made of complex, dynamic populations. Despite the importance to analyzing and modeling populations, existing notions of synchrony often lack rigorous definitions, may be specialized to a particular experimental system and/or measurement, or may have undesirable properties that limit their utility.
View Article and Find Full Text PDFThe effect of temporary CSF diversion modality on shunt-dependency following aneurysmal subarachnoid hemorrhage: A nationwide assessment.
J Clin Neurosci
December 2024
Department of Neurological Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Background: Aneurysmal subarachnoid hemorrhage (aSAH) carries a high economic cost and clinical morbidity in the United States. Beyond prolonged admissions and poor post-injury functional status, there is an additional cost of chronic shunt-dependent hydrocephalus for many aSAH patients. Adjuvant lumbar drain (LD) placement has been hypothesized to promote clearance of subarachnoid blood from the cisternal space, with an ultimate effect of decreasing shunt placement rates.
View Article and Find Full Text PDFHeuristic-based vehicle arrangement for ro-ro ships.
Sci Rep
December 2024
Information Science and Engineering School, Northeastern University, Shenyang, 110819, Liaoning, China.
In this paper, a two-level search strategy fused with an improved no-fit polygon algorithm and improved bat algorithm is proposed to obtain the layout points of multiple vehicles. Additionally, a space-time scheduling strategy is proposed using the Improved D*Lite Algorithm (ID*Lite) and improved Bezier curve to generate the trajectories of individual vehicles. Furthermore, a conflict resolution strategy is introduced to address the collision conflict problem during multi-vehicle scheduling.
View Article and Find Full Text PDFSaltwater intrusion and land subsidence destroy northern Nile Delta archaeological sites: An assessment using hydrochemical indices, SAR satellite imagery, and analytic hierarchy process (AHP).
Mar Pollut Bull
December 2024
Faculty of Engineering, Cairo University, 1 Gamaa Street, P.O. Box 12613, Giza, Egypt.
Archaeological sites in deltaic regions face increasing environmental threats. This study provides the first assessment of seawater intrusion and land subsidence impacts on archaeological sites in the Nile Delta through hydrochemical investigations, InSAR techniques, and multi-criteria decision analysis of 33 sites. The results reveal that 80.
View Article and Find Full Text PDFIdentification of the therapeutic potential of novel TIGIT/PVR interaction blockers based advanced computational techniques and experimental validation.
Biophys Chem
December 2024
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China; NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China. Electronic address:
The inhibition of the TIGIT/PVR interaction demonstrates considerable anticancer properties by enhancing the cytotoxic activity of natural killer (NK) and CD8+ T cells. However, the development of small molecule inhibitors that target TIGIT is currently limited. In this study, small molecules with the capacity to bind TIGIT and block the TIGIT/PVR interaction were screened through an advanced computational process, subsequently confirmed by blocking assays.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!