Recent advances of organ transplantation accelerated shortage of organs. Donor Action Program (DAP) was developed to establish a proper donation process in a hospital using total quality management methodology. It has been demonstrated effective in increasing donation and has been introduced in 23 countries. In Japan preliminary study demonstrated that (1) DAP could be implemented and was likely to increase donation in Japan, (2) Japanese healthcare staffs were likely to underestimate social needs and clinical results of transplantation and to be suspicious about brain death, (3) they had limited knowledge and experience in communicating with family members of the deceased, and their needs for education were not satisfied. In order to implement DAP in Japan, an organization which is responsible for data management and development for educational program should be considered with high priority.
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Curr Res Food Sci
December 2024
UMR 454 MEDIS, Microbiologie Environnement Digestif et Santé, Université Clermont Auvergne - INRAE, Clermont-Ferrand, France.
Associated to various illnesses, Western Diet (WD) is acknowledged to have deleterious effects on human gut microbiota, decreasing bacterial diversity, lowering gut bacteria associated to health (such as , while increasing those linked to diseases (e.g., ).
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June 2025
Glaucoma Service, Wills Eye Hospital, Philadelphia, PA, USA.
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View Article and Find Full Text PDFRedox Biol
January 2025
Department of Pediatrics, Peking University First Hospital, Beijing, 100034, PR China. Electronic address:
Background: The binding of endothelin-1 (ET-1) to endothelin type A receptor (ETAR) performs a critical action in pulmonary arterial smooth muscle cell (PASMC) proliferation leading to pulmonary vascular structural remodeling. More evidence showed that cystathionine γ-lyase (CSE)-catalyzed endogenous hydrogen sulfide (HS) was involved in the pathogenesis of cardiovascular diseases. In this study, we aimed to explore the effect of endogenous HS/CSE pathway on the ET-1/ETAR binding and its underlying mechanisms in the cellular and animal models of PASMC proliferation.
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Department of Transfusion Medicine, Sri Balaji Action Medical Institute, New Delhi, India.
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View Article and Find Full Text PDFAsian J Transfus Sci
August 2024
Asian Association of Transfusion Medicine, India Chapter, India.
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