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Case Report: Filamin C gene mutation associated with restrictive cardiomyopathy leading to heart transplantation.
Front Transplant
December 2024
Pediatric Cardiology and Adult with Congenital Heart Disease Unit, Instituto do Coração (InCor) do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Background: Cardiomyopathy is a disease that affects the myocardium and can be classified as dilated, restrictive, or hypertrophic cardiomyopathy. Among the subtypes, restrictive cardiomyopathy is characterized by restriction of ventricular filling and its uncommon cause is a disease due to mutation on Filamin C (FLNC) gene. Filamin C is an actin-binding protein encoded by FLNC gene and participates in sarcomere stability maintenance, which is expressed on the striated muscle.
View Article and Find Full Text PDFCase report: Cilioretinal artery occlusion combined with central retinal vein occlusion as the initial presentation of pulmonary arterial hypertension.
Front Med (Lausanne)
December 2024
Department of Ophthalmology, Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Article Synopsis
- PAH can cause serious ocular conditions like CRVO and CilRAO due to high blood pressure in the lungs affecting blood flow to the eyes.
- A 13-year-old girl with a history of heart surgery experienced sudden vision loss, with tests revealing both CRVO and CilRAO, along with signs of severe PAH.
- Treatment with Bosentan and traditional Chinese medicine led to significant vision improvement, highlighting the importance of addressing cardiovascular issues to prevent eye complications and the need for a comprehensive approach in such complex cases.
Acute Coronary Syndrome in a 40-Year-Old Male With Coronary Ectasia: A Case Report.
Cureus
December 2024
Zulekha Hospital, Intensive Care Unit, Sharjah, ARE.
Article Synopsis
- Coronary artery ectasia (CAE) is a rare condition usually found during coronary angiography and can increase the risk of blood clots.
- A 40-year-old male with acute coronary syndrome experienced a complete blockage in his ectatic left circumflex artery and the dominant right coronary artery.
- After thrombus aspiration restored normal blood flow, the case highlights the difficulties in treating acute coronary syndrome in patients with CAE and stresses the need for further research on effective treatment methods.
Transcatheter Aortic Valve Replacement in Hypertrophic Cardiomyopathy: A Systematic Review and Meta-Analysis.
Catheter Cardiovasc Interv
January 2025
Division of Cardiovascular Diseases, Bridgeport Hospital, Yale New Haven Health, Bridgeport, Connecticut, USA.
Background: The co-existence of severe aortic stenosis (AS) and hypertrophic cardiomyopathy (HCM) is not uncommon. Surgical intervention is the gold standard management. Patients with high surgical risk might undergo transcatheter aortic valve replacement (TAVR).
View Article and Find Full Text PDFUncommon etiology of ST-elevation myocardial infarction: Behçet's disease-induced coronary aneurysm.
J Invasive Cardiol
December 2024
University of Texas, MD Anderson Cancer Center, Houston, Texas. Email:
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