Objective: To determine the feasibility of achieving births using sperm retrieved from a solitary testis with cancer.

Design: Prospective clinical study of azoospermic men with testis cancer in a solitary testis.

Setting: Infertility patients in an academic environment.

Patient(s): Azoospermic men with previous history of orchiectomy and testis cancer in a remaining solitary testis.

Intervention(s): Viable sperm were retrieved by immediate microdissection of paratumor testicular tissue from orchiectomy specimen.

Main Outcome Measure(s): Live births were achieved using sperm from immediate microdissection of orchiectomy specimen with testis cancer.

Conclusion(s): Azoospermic men with cancer in a solitary testis have potential for fertility.

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Source
http://dx.doi.org/10.1016/j.fertnstert.2005.06.020DOI Listing

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