Objective: To determine whether vasectomy is associated with an increased long-term risk of cancer or cardiovascular disease.
Design: Analysis of database of linked statistical records of hospital admissions and deaths.
Setting: Health region in southern England.
Patient(s): Men aged 20-59 years who were admitted to a hospital for vasectomy.
Intervention(s): None.
Main Outcome Measure(s): Rates of cancer and cardiovascular disease compared with the corresponding rates in a reference cohort, expressed as a rate ratio.
Result(s): We found no elevation of risk, after vasectomy, of prostate cancer (rate ratio 0.74, 95% confidence interval [CI] 0.45-1.14) or other cancers. The rate ratio for coronary heart disease overall after vasectomy was 0.95 (95% CI 0.88-1.02); and the rate ratio > or =20 years after vasectomy was 0.98 (95% CI 0.80-1.19).
Conclusion(s): Our findings add to the evidence that vasectomy is not associated with an increase in the long-term risk of these diseases.
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| http://dx.doi.org/10.1016/j.fertnstert.2005.04.052 | DOI Listing |
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