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Antibiofilm effect of Nano chitosan and calcium hydroxide intracanal medications and their effects on the microhardness and chemical structure of radicular dentine.
BMC Oral Health
January 2025
Department of Endodontics, Faculty of Oral and Dental Medicine, Egyptian Russian University, Badr City, Egypt.
Background: Disinfection of the root canal system is a challenge to all clinicians, calcium hydroxide Ca(OH) one of the most popular intracanal medications used for this purpose, has some unwanted effects on dentine. This study aimed to investigate the antibiofilm effect of Nanochitosan (CSNPs) and Calcium hydroxide Ca(OH) intra canal medications and their effect on the microhardness and chemical structure of radicular dentine.
Methodology: A total of 52 extracted human mandibular premolars were used.
Application of Three Types of Scaffolds in Pulp Regeneration for Permanent Mature Teeth with Periapical Lesions: A Randomized Controlled Trial.
Eur Endod J
December 2024
Department of Pediatric Dentistry, Damascus University, Faculty of Dentistry, Damascus, Syria.
Objective: This study aimed to evaluate pulp regeneration by comparing the application of native chitosan-based scaffolds with enzymatically modified chitosan-based scaffolds in mature teeth with apical lesions, using clinical and radiographic assessments.
Methods: The eligibility criteria for this study were participants aged between 15-45 years, free from systemic diseases and with necrotic mature single-rooted teeth with periapical lesions. The teeth were equally and randomly allocated into three groups (1: 1: 1 allocation): Group A received treatment with a Blood Clot (BC) scaffold; Group B with a combination of Native Chitosan and Blood Clot (NCS+BC) scaffold; and Group C with Enzymatically-Modified Chitosan and Blood Clot (EMCS+BC) scaffold.
Cross-linked Arenga pinnata (Wurmb.) Merr. starch and chitosan with sodium trimetaphosphate: Structure, physicochemical properties and in vitro digestibility.
J Food Sci
December 2024
Institute of Light Industry and Food Engineering, Guangxi University, Nanning, China.
The inherent limitations of native starch considerably restrict its applications in the food industry. To enhance its processing properties, Arenga pinnata (Wurmb.) Merr.
View Article and Find Full Text PDFSynthesis of a chitosan-based superabsorbent polymer and its influence on cement paste.
Int J Biol Macromol
December 2024
Key Lab of Smart Prevention and Mitigation of Civil Engineering Disasters of the Ministry of Industry and Information Technology and Key Lab of Structures Dynamic Behavior and Control of the Ministry of Education, Harbin Institute of Technology, Harbin 150090, China; School of Civil Engineering, Harbin Institute of Technology, Harbin 150090, China. Electronic address:
To address the challenge of adaptability between cement-based materials and conventional superabsorbent polymers (sodium polyacrylate, Na-PA), a chitosan-based superabsorbent polymer (CSP) with high salt and alkaline resistance was synthesized, and the optimal synthesis process was determined by a single-factor method. The macroscopic performance and microstructure of CSP and Na-PA were compared, and their influences on cement paste were studied. The results show that CSP exhibits a gradual swelling process during water absorption, which is independent of the solution environment.
View Article and Find Full Text PDFFabrication of PLA-Based Nanoneedle Patches Loaded with Transcutol-Modified Chitosan Nanoparticles for the Transdermal Delivery of Levofloxacin.
Molecules
September 2024
Laboratory of Pharmaceutical Technology, Division of Pharmaceutical Technology, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Current transdermal drug delivery technologies, like patches and ointments, effectively deliver low molecular weight drugs through the skin. However, delivering larger, hydrophilic drugs and macromolecules remains a challenge. In the present study, we developed novel transdermal nanoneedle patches containing levofloxacin-loaded modified chitosan nanoparticles.
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