[The expression of COX-1 and COX-2 following brain injuries]. | LitMetric

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[The expression of COX-1 and COX-2 following brain injuries]. | LitMetric

[The expression of COX-1 and COX-2 following brain injuries].

Xue-rong Guo Yi-wu Zhou Yi-lie Ma

Fa Yi Xue Za Zhi

Faculty of Forensic Medicine, Huazhong University of Science & Technology, Wuhan 430030, China.

Published: August 2005

Cyclooxygenase (COX) is the obligate, rate-limiting enzyme for the conversion of arachidonic acid into prostaglandins, which mediate mitogenesis, apoptosis, angiogenesis, blood flow, secondary injury, and inflammation. COX is consist of 2 subtypes: COX-1 and COX-2. In recent years, there are a number of lines of evidence that COX-1 and COX-2 play a important in role brain injuries.

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