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Innovations in Nipple-areolar Complex Reconstruction: Evaluation of a New Prosthesis.
Plast Reconstr Surg Glob Open
January 2025
From the Department of Reconstructive Surgery and Hand Surgery, Azienda Ospedaliera Universitaria delle Marche, Ancona, Italy.
Background: The reconstruction of the nipple-areola complex (NAC) is a crucial step for completing breast restoration with patient satisfaction. Surgical reconstruction or tattooing of the NAC may not be preferable or feasible for some patients. There is no universal method for NAC that is ideal for every patient or clinical situation.
View Article and Find Full Text PDFThe feasibility of virtual reality therapy for upper extremity mobilization during and after intensive care unit admission.
PeerJ
January 2025
Department of Intensive Care, Medical Center Leeuwarden, Leeuwarden, Netherlands.
Introduction: Early mobilization reduces long-term muscle weakness after intensive care unit (ICU) admission, but barriers (e.g., anxiety, lack of motivation) may complicate patients' adherence to exercise.
View Article and Find Full Text PDFAdoptive cell therapy with tumor-infiltrating lymphocytes in combination with nivolumab in patients with advanced melanoma.
Immunooncol Technol
December 2024
Department of Biomedicine, University of Basel, Basel, Switzerland.
Background: Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TIL) is a personalized immunotherapy. The efficacy of TIL-ACT has been demonstrated prospectively in patients with advanced melanoma but is not limited to melanoma patients. Many patients are refractory to TIL-ACT, however, or their cancer becomes resistant.
View Article and Find Full Text PDFExpanding access to maggot containment dressings through redesign and innovation.
Int Wound J
January 2025
Applied BioSciences, Faculty of Science and Engineering, Macquarie University, North Ryde, New South Wales, Australia.
There are two major styles of maggot debridement dressings: (1) confinement dressings that form a cage around the wound, and (2) containment dressings that completely surround the maggots within a sealed porous bag. For producers and clinicians wanting to prepare containment dressings using readily available polyester bags, it is currently difficult to seal these bags without expensive high-temperature plastic welders. This study aimed to identify simple and affordable methods for sealing maggots within polyester net bags.
View Article and Find Full Text PDFCopper-Based Biomaterials for Anti-Tumor Therapy: Recent Advances and Perspectives.
Acta Biomater
January 2025
The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education of Xiangya Hospital and School of Basic Medical Science, Central South University, Changsha, Hunan 410013, China; Hunan Key Laboratory of Non-Resolving Inflammation and Cancer, The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China. Electronic address:
Copper, an essential trace element, is integral to numerous metabolic pathways across biological systems. In recent years, copper-based biomaterials have garnered significant interest due to their superior biocompatibility and multifaceted functionalities, particularly in the treatment of malignancies such as sarcomas and cancers. On the one hand, these copper-based materials serve as efficient carriers for a range of therapeutic agents, including chemotherapeutic drugs, small molecule inhibitors, and antibodies, allowing them for precise delivery and controlled release triggered by specific modifications and stimuli.
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