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Effect of Different Treatments on Retinal Thickness Changes in Patients With Multiple Sclerosis: A Review.
CNS Neurosci Ther
January 2025
Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Multiple sclerosis (MS) is an autoimmune disorder affecting the central nervous system, with varying clinical manifestations such as optic neuritis, sensory disturbances, and brainstem syndromes. Disease progression is monitored through methods like MRI scans, disability scales, and optical coherence tomography (OCT), which can detect retinal thinning, even in the absence of optic neuritis. MS progression involves neurodegeneration, particularly trans-synaptic degeneration, which extends beyond the initial injury site.
View Article and Find Full Text PDFPrediction of OCT contours of short-term response to anti-VEGF treatment for diabetic macular edema using generative adversarial networks.
Photodiagnosis Photodyn Ther
January 2025
Department of Ophthalmology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. Electronic address:
Diabetic macular edema (DME) stands as a leading cause for vision loss among the working-age population. Anti-vascular endothelial growth factor (VEGF) agents are currently recognized as the first-line treatment. However, a significant portion of patients remain insensitive to anti-VEGF, resulting in sustained visual impairment.
View Article and Find Full Text PDFMicroglia heterogeneity during neuroinflammation and neurodegeneration in the mouse retina.
Brain Struct Funct
December 2024
State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China.
Microglia play important roles in maintaining homeostasis and immunoreactive defense in the central nervous system including retina. To accomplish such a wide range of functions, microglia are highly heterogeneous. Dark microglia (DM) were recently identified by electron microscopy (EM).
View Article and Find Full Text PDFFrequency analyses of postural sway demonstrate the use of sounds for balance given vestibular loss.
Gait Posture
December 2024
Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Ear Institute, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
Purpose: To investigate how adults with unilateral vestibular hypofunction and healthy controls incorporate visual and auditory cues for postural control in an abstract visual environment.
Methods: Participants stood on foam wearing the HTC Vive, observing an immersive 3-wall display of 'stars' that were either static or dynamic (moving front to back at 32 mm, 0.2 Hz) with no sound, static white noise, or moving white noise played via headphones.
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