Clinical variables associated with early administration of antipsychotics in bipolar mania.

Prog Neuropsychopharmacol Biol Psychiatry

Department of Psychiatry, Kangnam St. Mary's Hospital, The Catholic University of Korea College of Medicine, 505 Banpo-Dong, Seocho-Gu, Seoul 137-701, Republic of Korea.

Published: January 2006

AI Article Synopsis

  • The study focused on the early use of antipsychotics for treating bipolar mania in 63 inpatients with bipolar I disorder at a specific hospital.
  • Factors such as the admission route and previous exposure to antipsychotics significantly influenced the timing of treatment based on regression analysis.
  • The findings indicate a potential link between certain clinical variables and quicker administration of antipsychotics, but further research is needed to validate these results.

Article Abstract

This study evaluated the clinical variables associated with the early administration of antipsychotics for the treatment of bipolar mania. 63 out of 97 inpatients with bipolar I disorder according to the DSM-IV criteria and who were consecutively admitted to the Kangnam St. Mary's Hospital, between September 2002 and March 2004, were included in the study. Regression analysis was run on the clinical variables in order to identify the factors affecting the early administration of antipsychotics. The route of admission and exposure to antipsychotics at the last follow-up were found to be associated with the early administration of antipsychotics (odds ratios=33.0 and 13.1, respectively). This study suggests that some clinical factors in bipolar mania might be linked to the earlier antipsychotic treatment. However, more studies will be needed to confirm this finding.

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Source
http://dx.doi.org/10.1016/j.pnpbp.2005.08.024DOI Listing

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