Activities of flucytosine, fluconazole, amphotericin B, and micafungin in a murine model of disseminated infection by Candida glabrata.

Antimicrob Agents Chemother

Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Carrer Sant Llorenç 21, 43201, Reus, Spain.

Published: November 2005

We compared the efficacies of amphotericin B, fluconazole, flucytosine, and micafungin in a systemic murine infection by three isolates of Candida glabrata. Amphotericin B showed the best results, although none of the drugs dramatically reduced mortality or tissue burden in liver or spleen.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280170PMC
http://dx.doi.org/10.1128/AAC.49.11.4757-4759.2005DOI Listing

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