Synthesis of homo-N-nucleoside with 1,2,4-triazole-3-carboxamide.

Nucleosides Nucleotides Nucleic Acids

Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742, Korea.

Published: December 2005

On the basis of potent biological activities of ribavirin and homo-N-nucleosides, a novel homo-N-1,2,4-triazole-3-carboxamide derivative 1 was synthesized starting from 2,3,5-tri-O-benzoylribofuranosyl-1-acetate as a potential antiviral agent.

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Source
http://dx.doi.org/10.1081/ncn-200059368DOI Listing

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