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Nicotine-magnesium aluminum silicate complexes processed by blending: Characterization for usage as drug carriers in mucoadhesive buccal discs.
Int J Pharm
August 2023
Division of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address:
Complexation of nicotine (NCT) and magnesium aluminum silicate (MAS) has been formed in the dispersions that required multiple preparation steps. In this study, physical blending was used to produce NCT-MAS complexes. NCT, a free-base liquid state form, was adsorbed onto the MAS granules, where the diffusion and intercalation of NCT molecules into the MAS silicate layers occurred.
View Article and Find Full Text PDFEfficient removal of Cd from aqueous solution with a novel composite of silicon supported nano iron/aluminum/magnesium (hydr)oxides prepared from biotite.
J Environ Manage
March 2022
School of Minerals Processing and Bioengineering, Central South University, Changsha, 410083, China; Faculty of Materials Metallurgy & Chemistry, Jiangxi University of Science & Technology, Ganzhou, Jiangxi, 341000, China. Electronic address:
Taking low cost silicate minerals to develop efficient Cd adsorption materials was favorable to the comprehensive utilization of minerals and remediation of environmental pollution. In this study, a composite of silicon supported nano iron/aluminum/magnesium (hydr)oxides was prepared with biotite by combining acid leaching and base precipitation process, which was used to remove Cd. Cd adsorption behaviors were in accordance of pseudo-second order kinetic model and Langmuir model, and the obtained maximal Cd adsorption capacity was 78.
View Article and Find Full Text PDFMagnesium Aluminium Silicate-Metformin Hydrochloride Complexes - The Use of Isothermal Calorimetry for Probing Clay and Drug Nanocomplexations.
Curr Drug Deliv
January 2022
School of Applied Sciences, Department of Pharmacy, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH,United Kingdom.
Background: Studying complexation between a wide variety of drugs and clay is of high importance in expanding the knowledge about controlled drug delivery and its exploitation. This study reports the use of isothermal calorimetry (ITC) in understanding the complexation process occurring between magnesium aluminium silicate (MAS) and metformin hydrochloride (MET), as a potentially controlled release drug delivery system.
Objectives: To fully characterise and understand the complexes formed between MAS and MET and how that might impact on controlled release systems.
Regional Control and Optimization of Heat Input during CMT by Wire Arc Additive Manufacturing: Modeling and Microstructure Effects.
Materials (Basel)
February 2021
School of Materials Science and Engineering, Inner Mongolia University of Technology, Hohhot 010051, China.
Wire arc additive manufacturing (WAAM) of aluminum-magnesium (Al-Mg) ER5356 alloy deposits is accomplished by cold metal transfer (CMT). During the process, the temperature change of the alloy deposits has a great influence on molding quality, and the microstructure and properties of alloy deposits are also affected by the complex thermal history of the additive manufacturing process. Here, we used an inter-layer cooling process and controlled the heat input process to attempt to reduce the influence of thermal history on alloy deposits during the additive process.
View Article and Find Full Text PDFSite-specific delivery of green tea coated aluminium magnesium silicate beads and studies on their effect against chicken coccidiosis.
IET Nanobiotechnol
December 2020
Translational Research Platform for Veterinary Biologicals, Centre for Animal Health Studies (CAHS), Tamil Nadu Veterinary and Animal Sciences University (TANUVAS), Chennai 600051, India.
In this report, the site-specific co-delivery of green tea/aluminium magnesium silicate (AMS) was reported and the specific target delivery was achieved orally. The new co-precipitation process was developed to synthesis the green tea/AMS hybrid complex and using energy-dispersive X-ray spectroscopy, Fourier-transform infrared spectroscopy and Raman confirmed its successful synthesis. The blood biocompatibility of the green tea/AMS was tested using chicken blood, and the compound is safe up to 500 mg/ml.
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