E Pluribus Unum: 3' end formation of polyadenylated mRNAs, histone mRNAs, and U snRNAs.

Mol Cell

Department of Biochemistry, School of Medicine, University of Washington, Seattle, Washington 98195, USA.

Published: October 2005

The 3' ends of almost all eukaryotic RNAs are generated by nucleolytic cleavage. Remarkably, three groups now demonstrate that similar or identical endonucleases of the metallo-beta-lactamase family generate the 3' ends of polyadenylated mRNAs, nonpolyadenylated histone mRNAs, and U snRNAs.

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http://dx.doi.org/10.1016/j.molcel.2005.10.009DOI Listing

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