The review of current informations connected with the non-antioxidative applications of vitamin E in therapy was performed. After explanation indispensable structural and nomenclatural questions, were have talked over was for above mentioned uses: biological activity of this vitamin, food sources and the metabolism. It was presented the systemic non-antioxidative functions and the resulting actions from here with range of prevention. The attention on day requirement, the states of deficiency and hypovitaminosis, and also on normal concentration in blood plasma was emphasized.
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J Physiol
January 2025
Centre for Discovery Brain Science, Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Edinburgh, UK.
JAMA Oncol
January 2025
Children's Wisconsin, Milwaukee.
Importance: Retrieval strategies for children, adolescents, and young adults with relapsed classic Hodgkin lymphoma (cHL) aim to maintain efficacy while minimizing long-term toxic effects. Children, adolescents, and young adults with low-risk, relapsed cHL may benefit from replacing high-dose chemotherapy and autologous stem cell transplant with less intensive involved-site radiotherapy (ISRT).
Objective: To evaluate a risk-stratified, response-adapted, transplant-free approach for treatment of children, adolescents, and young adults with low-risk relapsed cHL with nivolumab plus brentuximab vedotin (BV) followed by BV plus bendamustine for patients with suboptimal response and ISRT (30.
JAMA Ophthalmol
January 2025
The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Importance: While urban counties maintain higher densities of ophthalmologists than rural counties, the geographic distribution of ophthalmic surgical subspecialists has not yet been elucidated. A potential workforce discrepancy may impact the burden of care faced by rural surgeons.
Objective: To assess the geographic distribution of the ophthalmic subspecialist surgeon workforce and evaluate factors associated with practicing in rural areas.
JAMA Surg
January 2025
Departments of Surgery and Biomedical Engineering, University of Virginia School of Medicine, Charlottesville.
JAMA Oncol
January 2025
Department of Pediatric Oncology, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia.
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