Stoichiometric or catalytic quantities of simple 2 degrees amines greatly increase the rate of H-Zn exchange between ZnPh2 and a range of relatively non-acidic substrates, allowing for the convenient and direct preparation of alpha-functionalized organozincs.
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http://dx.doi.org/10.1039/b509190j | DOI Listing |
FEBS Lett
January 2025
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan.
Zinc transporters (ZnTs) act as H/Zn antiporters, crucial for zinc homeostasis. Brain-specific ZnT3 expressed in synaptic vesicles transports Zn from the cytosol into vesicles and is essential for neurotransmission, with ZnT3 dysfunction associated with neurological disorders. Ubiquitously expressed ZnT4 localized to lysosomes facilitates the Zn efflux from the cytosol to lysosomes, mitigating the cell injury risk.
View Article and Find Full Text PDFAcc Chem Res
October 2024
State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
ConspectusZinc-ion batteries (ZIBs) are highly promising for large-scale energy storage because of their safety, high energy/power density, low cost, and eco-friendliness. Vanadium-based compounds are attractive cathodes because of their versatile structures and multielectron redox processes (+5 to +3), leading to high capacity. Layered structures or 3-dimensional open tunnel frameworks allow easy movement of zinc-ions without breaking the structure apart, offering superior rate-performance.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
November 2024
Department of Chemistry and Centre for Pulse EPR spectroscopy (PEPR), Imperial College London, 82 Wood Lane, Shepherds Bush, London, W12 0BZ, UK.
Reaction of a molecular zinc-hydride [{(ArNCMe)CH}ZnH] (Ar=2,6-di-isopropylphenyl) with 0.5 equiv. of [Ni(CO)Cp] led to the isolation of a nickel-zinc hydride complex containing a bridging 3-centre,2-electron Ni-H-Zn interaction.
View Article and Find Full Text PDFChemistry
September 2023
Institute for Inorganic Chemistry, RWTH Aachen University, 52056, Aachen, Germany.
In the presence of TMEDA (TMEDA=N,N,N',N'-tetramethylethylenediamine), zinc dihydride reacted with germanium(II) compounds (BDI-H)Ge (1) and [(BDI)Ge][B(3,5-(CF ) C H ) ] (3) (BDI-H = HC{(C=CH )(CMe)(NAr) }, BDI = [HC(CMeNAr) ]; Ar = 2,6- Pr C H ) by formal insertion of the germanium(II) center into the Zn-H bond of polymeric [ZnH ] to give neutral and cationic zincagermane with a H-Ge-Zn-H core [(BDI-H)Ge(H)-(H)Zn(tmeda)] (2) and [(BDI)Ge(H)-(H)Zn(tmeda)][B(3,5-(CF ) C H ) ] (4), respectively. Compound 2 eliminated [ZnH ] giving diamido germylene 1 at 60 °C. Compound 2 and deuterated analogue 2-d exchanged with [ZnH ] and [ZnD ] in the presence of TMEDA to give a mixture of 2 and 2-d .
View Article and Find Full Text PDFChemistry
October 2022
Institute for Inorganic Chemistry, RWTH Aachen University, 52062, Aachen, Germany.
In the presence of TMEDA (N,N,N',N'-tetramethylethylenediamine), partially deaggregated zinc dihydride as hydrocarbon suspensions react with the gallium(I) compound [(BDI)Ga] (I, BDI={HC(C(CH )N(2,6-iPr -C H )) } ) by formal oxidative addition of a Zn-H bond to the gallium(I) centre. Dissociation of the labile TMEDA ligand in the resulting complex [(BDI)Ga(H)-(H)Zn(tmeda)] (1) facilitates insertion of a second equiv. of I into the remaining Zn-H to form a thermally sensitive trinuclear species [{(BDI)Ga(H)} Zn] (2).
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