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Cardiopulmonary arrest in liver transplantation surgery: Perioperative beta-blockade implication in the cirrhotic patient.
Rev Esp Anestesiol Reanim (Engl Ed)
January 2025
Hospital Universitario Gregorio Marañón, Madrid, Spain.
Liver transplantation (LT) has an incidence of intraoperative cardiopulmonary arrest (CPA) of around 5%. Patients who experience CPA during this procedure have a reduced survival rate of approximately 50%. Most CPAs occur during the neohepatic phase due to reperfusion syndrome, but this is not always the underlying cause, and a broad differential diagnosis must be performed.
View Article and Find Full Text PDFPerioperative management of patients with glioblastoma copresenting with pheochromocytoma: illustrative case.
J Neurosurg Case Lessons
November 2024
Division of Neurosurgery, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
Background: Undiagnosed pheochromocytoma can present with hemodynamic instability during surgical procedures. Here, the authors discuss a 69-year-old male with isocitrate dehydrogenase (IDH)-wildtype glioblastoma copresenting with undiagnosed pheochromocytoma, which, to the authors' knowledge, is the second reported case in the literature.
Observations: The patient presented to the emergency department with a 1-month history of coordination difficulties, progressive morning headache, and mild left-side weakness.
Variability in perioperative management of pheochromocytoma in Canada.
Can Urol Assoc J
September 2024
Western University, London, ON, Canada.
Introduction: Despite recent consensus guidelines, there is substantial variability in the management of pheochromocytomas. Our study aimed to characterize the current state of perioperative pheochromocytoma management by Canadian surgeons.
Methods: A 23-item online survey was sent to Canadian surgeons who perform adrenalectomies for pheochromocytoma.
The Society of Thoracic Surgeons Preoperative Beta Blocker Working Group Interim Report.
Ann Thorac Surg
February 2025
Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee.
Background: Atrial fibrillation (AF) occurs commonly after cardiac surgery and is associated with multiple adverse outcomes. Older randomized trials suggested that perioperative β- blockade reduced postoperative AF, and The Society of Thoracic Surgeons (STS) coronary artery bypass grafting (CABG) composite measure includes β-blocker administration preoperatively within 24 hours of surgery and at discharge. However, some more recent studies suggest preoperative β-blockade has limited value and question its continuation as an STS quality measure.
View Article and Find Full Text PDFMetabolomics of repetitive myocardial stunning in chronic multivessel coronary artery stenosis: Effect of non-selective and selective β1-receptor blockers.
J Physiol
July 2024
Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR, USA.
Article Synopsis
- Chronic coronary artery stenosis can cause myocardial dysfunction without heart attacks, often due to repetitive stunning or hibernation.
- A study using metabolomics on dogs showed that β-blockers like carvedilol and metoprolol can help improve heart function and metabolism in damaged tissues, particularly by influencing mitochondrial function.
- Carvedilol had more positive effects on recovery and mitochondrial health than metoprolol, suggesting that different β-blockers can have different impacts on heart health.
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