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November 2024

Section of Pediatric Surgery, Department of Surgery, University of Michigan, Michigan Medicine, C.S. Mott Children's Hospital, Ann Arbor, Michigan.

Introduction: Various randomized control trials in the pediatric population have shown no therapeutic advantage of video-assisted thoracoscopic surgery over fibrinolytic therapy (tissue plasminogen activator [tPA]) for empyema management. However, literature detailing changes in practice management and protocol implementation is limited. In 2018, we instituted clinical practice guidelines (CPGs) for empyema management utilizing tissue plasminogen activatorinstillation via a small bore chest tube as initial therapy.

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Pericardial effusion (PE) in pediatric population can be asymptomatic or a life-threatening event. Reports on neonates or preterm infants are scarce and generally related to pericardiocentesis of large amounts of PE in emergency situations.We describe a diagnostic pericardiocentesis in a preterm infant with small and loculated pericardial effusion and suspected cardiac mass.

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  • Pyruvate carboxylase (PC) deficiency is a rare genetic disorder that affects how the body metabolizes certain substances, inherited in an autosomal recessive manner.
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