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POLYPHARMACY AND CANCER: А NEW VISION FOR SKIN CANCER PATHOGENESIS-PHOTOTOXICITY AND PHOTOCARCINOGENICITY DUE TO NITROSAMINE CONTAMINATION DURING TELMISARTAN/ TAMSULOSIN INTAKE.
Georgian Med News
November 2024
4Department of Pathology, University of Virginia, Charlottesville, USA.
The toxicokinetics of nitrosamines remain a mystery to this day, though it appears that the role of nitrosamines in potentiating the generation of mutations required for the onset of skin cancer continues to be a significant concern. Nitrosamines are mutagens, genotoxic substances, and mediators of phototoxicity/carcinogenicity, whose long-term daily usage, in the context of polypharmacy, can result in the parallel appearance of heterogeneous forms of skin cancer: keratinocytic and melanocytic. But a number of clinical observations suggest that it is the nitrosamines that potentiate the multiple occurrences of skin cancer over the years, or recurrences of skin cancer localized in areas exposed to solar radiation.
View Article and Find Full Text PDFComment on "Glyphosate contamination in European rivers not from herbicide application?" By M. Schwientek, H. Rügner, S.B. Haderlein, W. Schulz, B. Wimmer, L. Engelbart, S. Bieger, C. Huhn; Water Research Volume 263, 1 October 2024, 122140, page 1-10.
Water Res
December 2024
KWR Water Research Institute, P.O. Box 1072, Nieuwegein 3430 BB, the Netherlands; Utrecht University of Applied Sciences, the Netherlands; Wageningen University and Research, the Netherlands. Electronic address:
INVITED REVIEW: Antimicrobial Resistance Genes in Milk: a 10-year-systematic review and critical comment.
J Dairy Sci
December 2024
Institute for Animal Breeding & Husbandry, Faculty for Agricultural & Nutritional Sciences, Kiel University, Germany.
Background: The occurrence of antimicrobial resistance genes in milk is eagerly discussed as a public health risk, and frequently investigated. Here, we perform a systematic review on the abundance of antimicrobial resistance genes in milk from primary production over a 10-year-period.
Objectives: We aimed to provide a comprehensive data set on known and emerging antimicrobial resistance genes in major mastitis pathogens, occurring worldwide in milk at primary production, and to critically discuss the relevance and constraints of these findings.
Lift-Out Specimen Preparation and Multiscale Correlative Investigation of Li-Ion Battery Electrodes Using Focused Ion Beam-Secondary Ion Mass Spectrometry Platforms.
ACS Appl Mater Interfaces
October 2024
Advanced Instrumentation for Nano-Analytics (AINA), Luxembourg Institute of Science and Technology (LIST), L-4422 Belvaux, Luxembourg.
Advanced characterization is paramount to understanding battery cycling and degradation in greater detail. Herein, we present a novel methodology of battery electrode analysis, employing focused ion beam (FIB) secondary-ion mass spectrometry platforms coupled with a specific lift-out specimen preparation, allowing us to optimize analysis and prevent air contamination. Correlative microscopy, combining electron microscopy and chemical imaging of a liquid electrolyte Li-ion battery electrode, is performed over the entire electrode thickness down to subparticle domains.
View Article and Find Full Text PDFRaman spectroscopy - a visit to the literature on plant, food, and agricultural studies.
J Sci Food Agric
August 2024
Instituto de Ciências Agrárias (ICIAG), Universidade Federal de Uberlândia (UFU), Uberlândia, Brazil.
Raman spectroscopy, a fast, non-invasive, and label-free optical technique, has significantly advanced plant and food studies and precision agriculture by providing detailed molecular insights into biological tissues. Utilizing the Raman scattering effect generates unique spectral fingerprints that comprehensively analyze tissue composition, concentration, and molecular structure. These fingerprints are obtained without chemical additives or extensive sample preparation, making Raman spectroscopy particularly suitable for in-field applications.
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