AI Article Synopsis

  • The study aimed to assess whether measurements of epiphyseal ossification centers can accurately estimate gestational age in fetuses.
  • Women with singleton pregnancies between 30-40 weeks participated, and researchers measured the dimensions of specific ossification centers to create a nomogram for fetal bone development.
  • Results showed a strong correlation between gestational age and the diameters of these centers, especially when combining measurements, suggesting that ultrasound imaging of ossification centers could serve as a reliable indicator of fetal age.

Article Abstract

Purpose: This study was conducted to verify the predictive value of epiphyseal ossification center measurements in estimating gestational age.

Methods: Women with singleton pregnancies of 30-40 weeks gestation (n = 377) were enrolled in this prospective study. The distal femoral, proximal tibial, and proximal humeral ossification centers were identified and measured. A nomogram of fetal bone development was created using the sum of the three diameters.

Results: Gestational age correlated well with the diameters of the distal femoral and the proximal tibial epiphyseal ossification centers but even better with the sum of the three ossification centers. Positive predictive values of the fetus having gestational age of at least 37 weeks when the sum of the three centers was 7, 11, and 13 mm were 82%, 94%, and 100%, respectively. A nomogram was created using the sum of the ossification centers for 30-40 weeks' gestational age.

Conclusions: Ultrasonographic visualization of the epiphyses ossification centers may be a useful marker of fetal gestational age.

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcu.20156DOI Listing

Publication Analysis

Top Keywords

ossification centers
24
gestational age
16
epiphyseal ossification
12
sum three
12
fetal gestational
8
distal femoral
8
femoral proximal
8
proximal tibial
8
created sum
8
ossification
7

Similar Publications

Photothermal Coating on Zinc Alloy for Controlled Biodegradation and Improved Osseointegration.

Adv Sci (Weinh)

January 2025

Department of Prosthodontics, Peking University School and Hospital of Stomatology, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, China.

Zinc (Zn) and its alloys are promising biomaterials for orthopedic applications due to their degradability and mechanical properties. Zn plays a crucial role in bone formation, but excessive early release may cause cytotoxicity and inhibit osseointegration. To solve this, we developed a near-infrared (NIR) light-controlled polycaprolactone/copper-sulfur (PCL/CuS) coating that slows degradation and enhances osseointegration of Zn alloys.

View Article and Find Full Text PDF

Differential expression of osteoblast-like cells on self-organized titanium dioxide nanotubes.

J Dent Sci

December 2024

Division for Globalization Initiative, Liaison Center for Innovative Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.

Background/purpose: Titanium dioxide nanotube (TNT) structures have been shown to enhance the early osseointegration of dental implants. Nevertheless, the optimal nanotube diameter for promoting osteogenesis remains unclear due to variations in cell types and manufacture of nanotubes. This study aimed to evaluate the differences in MC3T3-E1 and Saos-2 cells behavior on nanotubes of varying diameters.

View Article and Find Full Text PDF

The cranial mesenchyme, originating from both neural crest and mesoderm, imparts remarkable regional specificity and complexity to postnatal calvarial tissue. While the distinct embryonic origins of the superior and dura periosteum of the cranial parietal bone have been described, the extent of their respective contributions to bone and vessel formation during adult bone defect repair remains superficially explored. Utilizing transgenic mouse models in conjunction with high-resolution multiphoton laser scanning microscopy (MPLSM), we have separately evaluated bone and vessel formation in the superior and dura periosteum before and after injury, as well as following intermittent treatment of recombinant peptide of human parathyroid hormone (rhPTH), Teriparatide.

View Article and Find Full Text PDF

With the rise of bone tissue engineering (BET), 3D-printed HA/PCL scaffolds for bone defect repair have been extensively studied. However, little research has been conducted on the differences in osteogenic induction and regulation of macrophage (MPs) polarisation properties of HA/PCL scaffolds with different fibre orientations. Here, we applied 3D printing technology to prepare three sets of HA/PCL scaffolds with different fibre orientations (0-90, 0-90-135, and 0-90-45) to study the differences in physicochemical properties and to investigate the response effects of MPs and bone marrow mesenchymal stem cells (BMSCs) on scaffolds with different fibre orientations.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!