Objective: To evaluate health related quality of life (HRQoL) in a sample of patients suffering from chronic leg ulceration in Portugal.
Design: Questionnaire administered at baseline and following 12 weeks of treatment.
Setting: Community health clinics and out-patient departments of hospitals within the catchment area.
Participants: Patients suffering from chronic venous ulceration being cared for by community and hospital staff.
Methods: Patients entering the study were asked to complete the Nottingham Health Profile (NHP) Euroqol and Visual Analogue (VA) pain questionnaires at entry and after 12 weeks. Principal analysis compared final scores with those found at baseline, and compared results with UK based data.
Results: In all, 98 patients entered the study and completed the initial questionnaire, with 68 (69.3%) patients completing the follow up questionnaire. There were significantly (p<0.001) higher scores for the Portuguese patients compared with Portuguese normative data for all domains of the NHP (all p<0.001). Improvements were noted for all scores after 24 weeks. After 12 weeks bodily pain showed a significant improvement (mean difference [d]=10.5, p=0.003), with significant improvement in Euroqol (d=0.10, p=0.027). Energy and social isolation improved substantially in the 8 (11.8%) who healed, though not statistically, but VA pain score did (d=4.85, p<0.001).
Conclusions: Patients suffering from leg ulceration show modest improvements in perceived health following 12 weeks of care. Improvements in practice may enhance the magnitude of these improvements.
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Spine (Phila Pa 1976)
January 2025
Department of Neurological Surgery, Washington University, St. Louis, MO, USA.
Study Design: Prospective cohort study.
Objective: This study aims to define Substantial Clinical Benefit (SCB) thresholds for PROMIS physical function (PF) and pain interference (PI) in lumbar or thoracolumbar spine surgery population.
Summary Of Background Data: Patient-reported outcome measures (PROMs) are widely used in spine surgery to assess treatment efficacy.
Health Sociol Rev
January 2025
School of Social Sciences, University of New South Wales, Sydney, Australia.
Comfort is a central aspect of palliative care, encompassing the management of pain and symptoms, as well as how people feel and experience care. Comfort has been argued to be especially tenuous or transient in palliative care, as a constantly shifting set of bodily sensations and relations are anticipated and cared for. In this article, drawing on in-depth interviews and photo elicitation, we explore the accounts of patients, family carers, staff and volunteers from a palliative care service in Australia, to understand how care is configured and facilitated through everyday gestures of comfort.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
Health Management Center, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China.
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disorder that causes joint inflammation and affects quality of life. Appropriate physical activity can enhance joint function and lower cardiovascular disease risk. However, individuals with RA often have reduced physical activity levels, likely due to kinesiophobia, or fear of movement.
View Article and Find Full Text PDFJ Clin Orthop Trauma
March 2025
Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences, Nitte (Deemed to be University), Mangaluru, India.
Background: The effectiveness of intra-articular platelet-rich plasma (IA-PRP) injections for managing pain in knee osteoarthritis (KOA) remains inconsistent. Therefore, this study aimed to systematically review randomized controlled trials (RCTs) assessing the efficacy of IA-PRP.
Methods: A total of 21 studies meeting the inclusion criteria were selected from various scientific databases, all of which compared PRP to either a placebo or an active comparator, such as corticosteroids (CS), in the treatment of KOA.
Objectives: Endoscopic full-thickness resection for gastric submucosal tumors is gradually gaining popularity, and secure and amenable closure is key to its success. This study aimed to compare the reopenable clip over-the-line method with the purse-string method for defect closure after endoscopic full-thickness resection for gastric submucosal tumors.
Methods: This historical control trial included 37 consecutive patients with 37 gastric submucosal tumors, who underwent endoscopic full-thickness resection between January 2021 and July 2024.
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