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Alzheimers Dement
December 2024
University of Kentucky College of Medicine, Sanders-Brown Center on Aging, Lexington, KY, USA.
Background: Astrocytes are a glial cell type responsible for many protective functions in the brain. While they are primarily recognized for regulating synaptic activity, they're also essential for maintaining the neurovascular unit, and cerebral hyperperfusion during metabolic demand. Calcium signaling has been identified as a regulatory process for these functions.
View Article and Find Full Text PDFEvaluation of renal elasticity by shear wave elastography in children with Familial Mediterranean Fever.
Pediatr Nephrol
January 2025
Department of Radiology, Bursa Yuksek Ihtisas Egitim Ve Arastirma Hastanesi, Bursa, Turkey.
Background: Familial Mediterranean Fever (FMF) is a genetic disorder that can cause kidney damage. Shear wave elastography (SWE), a non-invasive method, was used to evaluate the decrease in renal tissue elasticity as a predictive parameter for amyloidosis. This study aimed to examine the changes in renal elasticity in patients with FMF using the renal SWE measurement method.
View Article and Find Full Text PDFPolyvinylidene Fluoride (PVDF)-Trimethylaluminum (TMA) Chemistry: First-Principles Investigation and Experimental Insights.
ACS Appl Mater Interfaces
January 2025
Materials Science and Engineering, Binghamton University, Binghamton, New York 13905, United States.
Atomic layer deposition (ALD) is a popular method of coating battery electrodes with metal oxides for improved cycling stability. While significant research has focused on the interaction between the reactive metal alkyl precursor and the electrode materials, little is known about the reactivity of the precursor toward other components of the battery electrode, such as the polymer binder. This study presents a combined computational and experimental investigation of the reaction between the popular polyvinylidene (PVDF) binder and the trimethylaluminum (TMA) precursor commonly used for coating AlO by ALD.
View Article and Find Full Text PDFSystemic and Cardiac Microvascular Dysfunction in Hypertension.
Int J Mol Sci
December 2024
Dipartimento di Biotecnologie e Scienze della Vita, ASST Sette Laghi, Università degli Studi dell'Insubria, 21100 Varese, Italy.
Hypertension exerts a profound impact on the microcirculation, causing both structural and functional alterations that contribute to systemic and organ-specific vascular damage. The microcirculation, comprising arterioles, capillaries, and venules with diameters smaller than 20 μm, plays a fundamental role in oxygen delivery, nutrient exchange, and maintaining tissue homeostasis. In the context of hypertension, microvascular remodeling and rarefaction result in reduced vessel density and elasticity, increasing vascular resistance and driving end-organ damage.
View Article and Find Full Text PDFPolydimethylsiloxane loaded capsaicin afflicts membrane integrity, metabolic activity and biofilm formation of nosocomial pathogens.
Microb Pathog
January 2025
Biofouling and Biofilm Processes Section, Water and Steam Chemistry Division, Bhabha Atomic Research Centre Facilities, Kalpakkam, 603 102, India; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400 094, India. Electronic address:
Biofilms constitute 80 % of all nosocomial infections associated with invasive medical devices. Polydimethylsiloxane, a highly elastic, inert, non-reactive, biocompatible silicone polymer is widely used as implant biomaterial due to its non-toxic and low-immunogenic nature. Owing to its hydrophobicity, PDMS suffers from microbial adhesion.
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