1.034 inhabitants (270 men, 459 women and 305 children) were examined in Racha region (North-western Georgia) on endemic goiter at the age from 1 to 75. The investigated population was selected by randomized method. Diagnostic criteria for the evaluation of the degree of endemic goiter were based on the data of palpation and ultrasonography. In children iodine excretion by urine was also determined. Obtained data were analyzed by means of computer program Epi info-6. Prevalence of endemic goiter in examined population was 62,4% (45,2% in men, 72,1% in women and 62,9% in children). The highest spreading of the endemic goiter is noticed in the 21-30 year age group among women (78,8%). The main form of endemic goiter in Racha region is euthyroid diffuse goiter (56,1%). High index of spreading of endemic goiter in Racha region is caused by iodine deficiency along with irrational feeding and genetic factors.
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J Nutr
December 2024
Department of Nutrition and Food Hygiene, Tianjin Medical University, Tianjin, China; Tianjin Medical University General Hospital, Tianjin, China; Tianjin Environmental, Nutrition and Public Health Center, Tianjin, China. Electronic address:
Background: Both iodine deficiency and iodine excess can harm the thyroid glands during pregnancy. In areas without iodine fortification, the relationship between the water iodine concentration (WIC) and thyroid disease in pregnant women requires further investigation.
Objectives: The aim of this study was to evaluate the relationship between WICs and the prevalence of thyroid disease in pregnant women residing in areas with high WICs without access to iodized salt.
J Med Case Rep
November 2024
Department of Otolaryngology, Head and Neck Surgery, Moulay El Hasssan Military Hospital, Guelmim, Morocco.
Background: Hydatid disease, a parasitic infection caused by the larval form of Echinococcus granulosus, infrequently involves the thyroid gland, whether through direct invasion or hematogenous spread.
Case Presentation: We report the case of a 62-year-old female patient from Morocco who presented with an anterior cervical mass, initially suspected to be a goiter. A histopathological evaluation of the thyroidectomy specimen identified the presence of a hydatid cyst.
Front Endocrinol (Lausanne)
November 2024
Key Lab of Etiology and Epidemiology, National Health Commission & Education Bureau of Heilongjiang Province (23618504), Key Laboratory of Trace Elements and Human Health, Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, China.
Goiter related to excessive iodine nutrition remains a significant public health issue in some countries. There has been no reported study on long noncoding RNAs (lncRNAs) related to goiters. In this study, goiter was induced by drinking water with excess iodine for 10 or 20 weeks in Kunming mice.
View Article and Find Full Text PDFHeliyon
November 2024
Department for Environmental Health (Endemic Disease Control and Prevention), Jiangsu Provincial Center for Disease Control and Prevention, Jiangsu Road 172, 210009 Nanjing, PR China.
Introduction: With advancements in detection equipment and an increase in the frequency of examinations, thyroid nodules and goiter in children have garnered attention.
Objective: This study aims to determine the effects of high iodine and fluoride exposure on thyroid nodules and goiter in school-aged children.
Methods: We recruited children aged 8 to 12 from rural Jiangsu, China, based on the concentrations of iodine and fluoride in local drinking water and urine.
J Nutr
December 2024
Section of Endocrinology, Diabetes, and Nutrition, Boston University Chobanian and Avedisian School of Medicine, Boston, MA, United States. Electronic address:
Iodine is essential for the synthesis of thyroid hormones, which regulate cell metabolism, growth, and development. Although iodine deficiency (ID) causes adverse health effects across the lifespan, it is particularly problematic in pregnancy, when it can lead to irreversible fetal brain damage. A high prevalence of severe ID, manifesting as endemic goiter and cretinism, predated the arrival of European explorers in the Americas.
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