The target N6-ferrocene substituted NAD derivatives (ferrocene-labeled NAD, Fc-NAD) were synthesized as an electron-relay NAD cofactor. The synthesized NAD derivatives possessed some biological activities as substrates in the alcohol dehydrogenase systems. The oxidation current depended on both addition of ethanol and spacer length of Fc-NAD.
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| http://dx.doi.org/10.1016/S1389-1723(04)70155-3 | DOI Listing |
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