A 5-year-old boy with 7 q trisomy received general anesthesia for tracheostomy. He was born with multiple morphological malformations including anomalies of ears, eyes, face and vertebral, accompanying difficulty in tracheal intubation. At first we inserted a laryngoscope under awake condition to estimate the difficulty in intubation. Then, we performed intubation under sevoflurane-N2O-O2 anesthesia. After intubation, there was no problem during the operation. A child with chromosome abnormality has multiple malformations and we should be ready for possible difficulties.

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