Changes in the natural course of Trypanosoma cruzi infection have been associated with immunosuppression. We report here a case of the reactivation of Chagas' disease in a patient with non-Hodgkin's lymphoma with gastric, oesophageal and laryngeal involvement. This is the first report describing the involvement of the larynx by T. cruzi.
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http://dx.doi.org/10.1016/j.trstmh.2005.07.005 | DOI Listing |
Transpl Immunol
December 2024
Graduate Program in Health Sciences, Faculdade de Medicina de São José de Rio Preto (FAMERP), São José do Rio Preto, SP 15090-000, Brazil; Universidade de Ribeirão Preto (UNAERP), Ribeirão Preto, SP 14096-900, Brazil.
Objective: This study aimed to assess the expression patterns of galectin-3 (Gal-3) and NLRP3 in heart transplant recipients according to the presence of reactivated Trypanosoma cruzi infection or allograft rejection in Chagas and non-Chagas heart transplant recipients.
Methods: Gal-3 and NLRP3 expression levels were analyzed in endomyocardial biopsies from 31 heart transplant recipients, including 16 patients with chronic Chagas disease (ChD) and 15 without ChD. Samples were evaluated during periods of graft rejection or ChD reactivation, characterized by intense myocardial cellular infiltrate, and after remission of the infiltrate, classified by histopathological severity.
Open Forum Infect Dis
December 2024
Department of Pharmacology & Toxicology, University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Braz J Infect Dis
December 2024
Departamento de Parasitología, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica; Centro de Investigación en Enfermedades Tropicales (CIET), Universidad de Costa Rica, San José, Costa Rica. Electronic address:
American trypanosomiasis or Chagas disease is a vector-borne infection caused by the protozoan parasite Trypanosoma cruzi, characterized by acute and chronic phases; reactivations due to immunosuppression can occur. In this case report, we confirm the presence of trypomastigotes of T. cruzi in a patient with neurologic manifestations.
View Article and Find Full Text PDFInt J Mol Sci
October 2024
Laboratory for Applied Science and Technology in Health, Carlos Chagas Institute, Oswaldo Cruz Foundation (Fiocruz), Curitiba 81350-010, Brazil.
Transpl Infect Dis
October 2024
International Health Unit Vall d'Hebron-Drassanes, Infectious Diseases Department, Vall d'Hebron University Hospital, PROSICS Barcelona, Barcelona, Spain.
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