AI Article Synopsis
- Bax mRNA levels in the fetal rat brain stem rise by day 40 and then decline, while Bcl-XL mRNA reaches adult levels in about a month.
- In the cerebral cortex, Bax mRNA decreases from day 8 to day 90, while Bcl-XL mRNA remains stable.
- The Bcl-XL/Bax mRNA ratio suggests that cortical cells are more prepared for apoptosis compared to brain stem cells.
Article Abstract
Bax mRNA level in fetal rat brain stem increases by day 40 of life and then decreases, while level of Bcl-XL mRNA reaches the adult value over one month. Bax mRNA level in the cerebral cortex decreases from day 8 to day 90 of life, while Bcl-XL mRNA level does not change. Judging from Bcl-XL/Bax mRNA ratio, cortical cells exhibit higher readiness to apoptosis than brain stem cells.
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| http://dx.doi.org/10.1007/s10517-005-0383-2 | DOI Listing |
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