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Surviving not Thriving After Gunshot Wound: Prospective Study of Quality of Life, PTSD, and Employment.
J Surg Res
March 2025
Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.
Introduction: Psychosocial morbidity, including posttraumatic stress disorder (PTSD), depression, and failure to return to work, is common following gunshot wounds (GSWs). GSW victims with retained bullets experience increased rates of elevated blood lead, putting patients at risk for toxic effects on cognition and mood. This pilot study was performed to examine associations between retained bullets and employment and psychosocial outcomes after GSW.
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Indian J Otolaryngol Head Neck Surg
January 2025
Otorhinolaryngology, Head and Neck Surgery Department, Royal Medical Service, Manama, Bahrain.
Unlabelled: Congenital nasal pyriform aperture stenosis (CNPAS) is a rare disorder that causes airway obstruction in newborns and children. Patients with CNPAS mainly present with nasal obstruction, respiratory distress, feeding difficulties, and/or failure to thrive. Here, we present the case of a 1-day old male baby born with tachypnea, nasal obstruction, and congestion.
View Article and Find Full Text PDFGFAP mutation and astrocyte dysfunction lead to a neurodegenerative profile with impaired synaptic plasticity and cognitive deficits in a rat model of Alexander disease.
eNeuro
March 2025
Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA.
Alexander disease (AxD) is a rare neurological disorder caused by dominant gain-of-function mutations in the gene for glial acidic fibrillary protein (). Expression of mutant protein results in astrocyte dysfunction that ultimately leads to developmental delay, failure to thrive, and intellectual and motor impairment. The disease is typically fatal, and at present there are no preventative or effective treatments.
View Article and Find Full Text PDFClinical, laboratory, and therapeutic differences between immunoglobulin E-mediated and non-immunoglobulin E-mediated cow's milk protein allergy in children.
World J Clin Pediatr
March 2025
Public Health Directorate, Ministry of Health, Manama 26671, Bahrain.
Background: Although breast milk is ideal for newborns, in some cases, it is replaced with cow's milk, which contains proteins that increase the risk of cow's milk protein allergy (CMPA).
Aim: To evaluate CMPA prevalence in Bahrain and compare clinical characteristics of children with immunoglobulin E (IgE)- and non-IgE-mediated CMPA.
Methods: This retrospective cohort study examined children with CMPA diagnosed at the pediatric gastroenterology outpatient clinic of the Salmaniya Medical Complex, Bahrain, between 2014 and 2022, and assessed CMPA prevalence.
Strategies for early detection and detailed characterization of oral lesions and head and neck squamous cell carcinoma in Fanconi anemia patients.
Cancer Lett
March 2025
Department of Radiation Oncology, Centre François Baclesse, Caen, France, Laboratoire de Physique Corpusculaire IN2P3/ENSICAEN/CNRS UMR 6534, Normandie Université, Caen, France.
Fanconi Anemia (FA) is an inherited disorder associated with profound DNA repair defects, marked by failure to thrive, congenital malformations, progressive bone marrow failure (BMF), and an increased susceptibility to cancer. Clinical manifestations of FA vary widely, with BMF and clonal evolution predominantly affecting younger individuals, while adults are more frequently presenting with solid tumors. Individuals with FA are at a 500-fold increased risk of developing head and neck squamous cell carcinoma (HNSCC), which tends to appear at a median age of 30 years, often at advanced stages with only a 57 % two-year survival rate.
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