Objective: To analyze the effects of various slicing schemes on the detection of metastases in lymph nodes.
Study Design: Use of an advanced computer simulation tool.
Results: Bisectioning along the longitudinal axis is an inadequate approach. Slicing ellipsoid lymph nodes along their longitudinal axis also results in a lower rate of detecting metastases since metastatic deposits have a predilection to localize subcapsularly.
Conclusion: Ellipsoid lymph nodes must be sliced perpendicular to the longest axis to increase the rate of detecting metastases.
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