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Molecular genetic analysis for a novel Ael allele of the ABO blood group system. | LitMetric

AI Article Synopsis

  • The ABO blood group system is crucial for blood transfusions, especially in clinical settings.
  • Previous research indicates that the ABO gene has unique genetic traits in the Chinese population.
  • This study identifies a new allele in an individual from a family diagnosed with the rare Ael subgroup after conducting a molecular genetic analysis.

Article Abstract

The ABO blood group is the most important system in clinical transfusion medicine. Previous studies on the genetic base of the common ABO group and some rare ABO subgroups have suggested that the molecular genetic background of the ABO gene in the Chinese population has specific character. In this study, we carried out a molecular genetic analysis of a family with an individual diagnosed as Ael subgroup by serological tests. A novel allele was identified in our A subgroup cases.

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Source
http://dx.doi.org/10.1007/s10038-005-0308-yDOI Listing

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