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Maternal mortality in Italy estimated by the Italian Obstetric Surveillance System.
Sci Rep
December 2024
National Centre for Diseases Prevention and Health Promotion, Istituto Superiore di Sanità, Rome, Italy.
This study aimed to calculate Italy's first national maternal mortality ratio (MMR) through an innovative record-linkage approach within the enhanced Italian Obstetric Surveillance System (ItOSS). A record-linkage retrospective cohort study was conducted nationwide, encompassing all women aged 11-59 years with one or more hospitalizations related to pregnancy or pregnancy outcomes from 2011 to 2019. Maternal deaths were identified by integrating data from the Death Registry and national and regional Hospital Discharge Databases supported by the integration of findings from confidential enquiries conducted through active surveillance.
View Article and Find Full Text PDFPurpose: Based on an initial hypothesis that the abdominal radiograph is rarely useful in the radiographic shunt series (SS), this study sought to determine which components of the SS are useful in identifying and diagnosing shunt dysfunction. This enquiry broadened to evaluate which modalities were most clinically useful in patients who ultimately underwent shunt revision for their suspected dysfunction.
Methods: Arm1: Abdominal radiographs (AXR) performed over a 2-year period were reviewed retrospectively to identify shunt abnormalities.
Performance of the MOLES and TFSOM-DIM scores in classifying choroidal nevi and melanoma.
Sci Rep
November 2024
Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Article Synopsis
- - Choroidal nevi are benign eye lesions often found during eye exams, and while they rarely become malignant, they are frequently referred to specialists, leading to a backlog in care for patients with more serious conditions.
- - The MOLES score was developed to help non-specialists distinguish between choroidal nevi and melanoma, demonstrating high specificity (96%) and sensitivity (100%) in a study involving nearly 700 patients.
- - Combining the MOLES score for initial screenings with the TFSOM-DIM score for assessing tumor progression can improve patient management and referrals, guiding both non-experts and specialists in monitoring these eye conditions.
Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy.
Cochrane Database Syst Rev
November 2024
Departement de Biostatistique et Informatique Médicale, Hôpital Saint Louis, 75475 Paris, France.
Article Synopsis
- Excessive daytime sleepiness is a frequent issue in myotonic dystrophy, prompting the use of psychostimulants to treat hypersomnia in these patients.
- The study aimed to evaluate the effectiveness of psychostimulants in alleviating hypersomnia symptoms in individuals with myotonic dystrophy, using data from randomized controlled trials.
- A total of six trials involving 136 adult participants were reviewed, suggesting a positive short-term impact of psychostimulants on improving wakefulness, with most trials showing low risk of bias.
NSW cannabis medicines advisory service retrospective enquiry analysis to inform clinical guidance resource development.
Neuropsychopharmacol Rep
March 2025
Australian Centre for Cannabinoid Clinical and Research Excellence, Newcastle, New South Wales, Australia.
Background: An innovative New South Wales government funded statewide Cannabis Medicines Advisory Service (CMAS) operated between January 2018 and June 2022. The service provided comprehensive patient-specific and evidence-based information to support health professionals in prescribing and patient care decisions. This study aimed to describe real-world data collected by CMAS.
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