Objective: The optimal extraction technology of Fengshitongbi capsule was investigated in this study.

Methods: Orthogonal tests were employed for optimum of extraction technology, the determination of the contents of Chlorogenic acid and Sinomenine were gained by HPLC and TLC-scanning respectively.

Results: Six volume of water,extracting 3 times with half an hour each time, and seven volume of 70% ethanol, extracting two times with one and a half hour each time were considered the optimum extraction technology of Flos Lonicerae and Caulis Sinomenii as well as Rhizoma Smilacis Glabrae respectively.

Conclusion: The considerable extraction rate of active components in the drugs is achieved by applying the selected technology.

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