AI Article Synopsis
- The study focused on a stirred-tank fermenter using a combination of a regular agitation impeller and a foam-breaking impeller on the same shaft to improve performance with low-viscosity foaming liquids.
- Changing the agitation impeller from a conventional six-blade turbine to a rod impeller enhanced the efficiency of the foam-breaking impeller significantly.
- The new method not only provided a higher oxygen-transfer rate, about five times greater than traditional foam-control methods using chemicals but also reduced the cultivation time of yeast, Saccharomyces cerevisiae K-7, leading to quicker cell concentration results.
Article Abstract
This study examined a stirred-tank fermenter (STF) containing low-viscosity foaming liquids with an agitation impeller and foam-breaking impeller mounted on the same shaft. Results showed that the performance of the foam-breaking impeller can be improved by changing a conventional six-blade turbine impeller into a rod impeller as the agitation impeller. The volumetric oxygen-transfer coefficient, kLa, in the mechanical foam-control method (MFM) using a six-blade vaned disk as the foam-breaking impeller in the STF with the rod impeller was approximately five times greater than that of the chemical foam-control method (CFM) adding an anti-foaming agent in the STF with the six-blade turbine impeller. Application of the present method to the cultivation of Saccharomyces cerevisiae K-7 demonstrated that the cultivation time up to the maximum cell concentration was remarkably shorter than that achieved using a conventional CFM.
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| http://dx.doi.org/10.1007/s00449-005-0028-x | DOI Listing |
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