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Opioids for non-operable osteoarthritis and soft-tissue rheumatism. | LitMetric

Reviews of oral opioid trials have shown that many side-effects need to be considered when treating patients with non-operable osteoarthritis and soft-tissue problems. European and American guidelines recommend their use with or without paracetamol. The controversy surrounding the use of non-steroidal anti-inflammatory drugs/cyclo-oxygenase-2 inhibitors is limiting physician and patient choices. There is a great need for alternative medication or ways of using current compounds.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257452PMC
http://dx.doi.org/10.1186/ar1817DOI Listing

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