The paper reviews the studies dealing with cerebral ischemia and neuroprotection. On this basis, the authors make conclusions on the perspectives of development of this direction and indicate the difficulties investigators and practitioners face in solving the problems in the protection of the brain from local and global ischemic lesion. Current views of the effectiveness of drugs and procedures used in daily practice and the authors' own experience in solving this topical anesthesiological and resuscitative problem are given.

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