Microbiological characteristics of medically important Trichosporon species.

Mycopathologia

Department of Dermatology/Research Center of Medical Mycology, Peking University First Hospital, Beijing, PR China.

Published: October 2005

Trichosporon species are opportunistic pathogens associated with a high mortality rate in immunocompromised patients. Disseminated trichosporonosis is uncommon but reports are increasing. In this study, using 16 stock clinical isolates of suspected Trichosporon species and 4 known Trichosporon strains, we investigated the morphology, physio-biochemistry, molecular biology and antifungal susceptibility characteristics of these Trichosporon spp. and discovered that ITS sequence-based identification is a rapid and accurate identification alternative to most phenotypic or physio- biochemical methods. In vitro antifungal susceptibility tests showed high amphotericin B, itraconazole and terbinafine MIC value in these Trichosporon strains.

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http://dx.doi.org/10.1007/s11046-005-0112-4DOI Listing

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