A novel spin trap for targeting sulfhydryl-containing polypeptides.

Chem Commun (Camb)

State Key Laboratory for Structural Chemistry of Unstable Species, Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100080, China.

Published: October 2005

A novel spin trap containing an iodoacetamide group has been synthesized and then used to target polypeptides, i.e. glutathione and bovine serum albumin, by which the resulting covalently bonded bioconjugates exhibit great potential for the application of spin trapping of transient radicals in biological systems.

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Source
http://dx.doi.org/10.1039/b509903jDOI Listing

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