AI Article Synopsis
- The cerebral cortex is connected to the basal ganglia and cerebellum, which are key subcortical structures involved in brain function.
- Research using rabies virus tracing in macaques reveals a two-step pathway connecting the cerebellum's dentate nucleus to the basal ganglia's striatum.
- This finding helps to address the longstanding question of how cerebellar and basal ganglia circuits interact within the brain.
Article Abstract
The cerebral cortex is interconnected with two major subcortical structures: the basal ganglia and the cerebellum. How and where cerebellar circuits interact with basal ganglia circuits has been a longstanding question. Using transneuronal transport of rabies virus in macaques, we found that a disynaptic pathway links an output stage of cerebellar processing, the dentate nucleus, with an input stage of basal ganglia processing, the striatum.
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| http://dx.doi.org/10.1038/nn1544 | DOI Listing |
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