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Inhibition of lipid droplet accumulation in macrophages by triterpenoids produced from Torametes orientaris. | LitMetric

Inhibition of lipid droplet accumulation in macrophages by triterpenoids produced from Torametes orientaris.

Biol Pharm Bull

Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University; Tokyo 108-8641, Japan.

Published: October 2005

AI Article Synopsis

Article Abstract

Four triterpenoids 1-4 isolated from the fruit body of Torametes orientaris were found to inhibit lipid droplet accumulation in macrophages. From the biochemical analysis, compounds 2 and 3 inhibited selectively cholesteryl ester synthesis in macrophages, while compounds 1 and 4 showed inhibition of both cholesteryl ester and triacylglycerol syntheses.

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Source
http://dx.doi.org/10.1248/bpb.28.1925DOI Listing

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