Efforts directed to identifying potent HIV protease inhibitors (PI) have yielded a class of compounds that are not only very active against wild-type (NL4-3) HIV virus but also very potent against a panel of PI-resistant viral isolates. Chemistry and biology are described.
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| http://dx.doi.org/10.1016/j.bmcl.2005.08.072 | DOI Listing |
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