The investigation included the study of 68 kidneys obtained from the persons of different age which died from mechanical asphyxia (control group) and 110 kidneys from the patients which died from cardiovascular failure that developed against a background of an ischemic heart disease, atherosclerosis, hypertension and their combinations. The studies were conducted using the complex of methods, which included macromicroscopic, histological, scanning electron microscopy and morphometry. In the patient group, vessel tortuosity, microvaricosities, contour irregularities and vessel deformations were found. Diameter of the vascular glomeruli and their number were reduced. Most pronounced changes in renal microvascular architectonics were detected in essential and renal hypertension, least expressed--in atherosclerosis with prevalent lesions in abdominal aorta. The disturbances of microcirculatory bed included juxtamedullary shunting, and excessive plethora or significant deterioration of blood supply to both cortex and medulla.
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