[The relationship between adenoids hypertrophy and secretory otitis media].

Objective: To investigate the relationship between immune status of adenoids and secretory otitis media (SOM).

Method: All the 76 cases of SOM were divided into 2 groups: recurrent group (46 cases) and control group (30 cases whose occurrence was less than 3 times). The manifestation of CD45RO, CD20, PCNA and BCL-2 in adenoids was detected with ultrasensitive (TM)S-P immunohistology.

Result: The expression of CD44Ro, CD20, PCNA and BCL-2 in recurrent group was significantly higher than that in control group (P < 0.05 or P < 0.01).

Conclusion: In adenoid tissues of recurrent SOM patients, the activities of lymphocytes and cells in hypertrophic status increase, the adenoids enlarge and local immunity enhances. Therefore, adenoidectomy for SOM patients should be carried out as early as possible.