AI Article Synopsis
- A 56-year-old man had a meningioma causing a visible mass on his forehead and eye bulging, with CT scans showing hyperostosis but no initial signs of a tumor.
- Follow-up imaging revealed an intracranial mass and hyperostosis that extended outside the skull, leading to surgery where the tumor was removed.
- Histological studies confirmed it was a rhabdoid meningioma, but most of the surrounding hyperostotic bone showed no tumor cells, suggesting that other mechanisms, rather than direct tumor invasion, may explain the hyperostosis.
Article Abstract
A 56-year-old man presented with a meningioma associated with hyperostotic bone containing little tumor cell infiltration. The patient presented with a growing mass on his right forehead and exophthalmos. Computed tomography (CT) taken 4 years previously revealed only hyperostosis without intracranial lesion. Repeat CT revealed an enhanced intracranial mass with overlying diffuse hyperostosis extending extracranially. The tumor and affected bone were widely removed. Histological examination confirmed rhabdoid meningioma in the intracranial and extracranial lesion. However, most of the hyperostotic bone showed no tumor cell infiltration. The cause of hyperostosis associated with meningioma is unclear, but tumor invasion is the generally accepted cause. In this case, hyperostosis occurred without tumor cell infiltration so another mechanism was probably involved. The extracranial extension occurred despite the disproportionately small tumor without global tumor cell infiltration of the bone or bony erosion.
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| http://dx.doi.org/10.2176/nmc.45.480 | DOI Listing |
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