AI Article Synopsis
- The study confirms previous findings of quantitative trait loci (QTL) associated with fatness traits through the analysis of an advanced intercross line (AIL) across multiple generations.
- Significant QTL for abdominal fat weight (AFW), percentage abdominal fat (AF%), and various body weights at different ages were identified on chromosomes 1, 3, 15, and 27 in the generation 9 (G(9)) population.
- Chromosomes 4 and 18 showed no significant evidence for QTL, while other chromosomes exhibited suggestive evidence for traits related to fatness and body weight.
Article Abstract
In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27. The AIL was created by random intercrossing in each generation from generation 2 (G(2)) onwards until generation 9 (G(9)) was reached. QTL for abdominal fat weight (AFW) and/or percentage abdominal fat (AF%) on chromosomes 1, 3 and 27 were confirmed in the G(9) population. In addition, evidence for QTL for body weight at the age of 5 (BW5) and 7 (BW7) weeks and for the percentage of intramuscular fat (IF%) were found on chromosomes 1, 3, 15, and 27. Significant evidence for QTL was detected on chromosome 1 for BW5 and BW7. Suggestive evidence was found on chromosome 1 for AFW, AF% and IF%, on chromosome 15 for BW5, and on chromosome 27 for AF% and IF%. Furthermore, evidence on the chromosome-wise level was found on chromosome 3 for AFW, AF%, and BW7 and on chromosome 27 for BW5. For chromosomes 4 and 18, test statistics did not exceed the significance threshold.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697231 | PMC |
| http://dx.doi.org/10.1186/1297-9686-37-3-215 | DOI Listing |
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Article Synopsis
- The study confirms previous findings of quantitative trait loci (QTL) associated with fatness traits through the analysis of an advanced intercross line (AIL) across multiple generations.
- Significant QTL for abdominal fat weight (AFW), percentage abdominal fat (AF%), and various body weights at different ages were identified on chromosomes 1, 3, 15, and 27 in the generation 9 (G(9)) population.
- Chromosomes 4 and 18 showed no significant evidence for QTL, while other chromosomes exhibited suggestive evidence for traits related to fatness and body weight.
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