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Role of Ciliary Neurotrophic Factor in Angiotensin II-Induced Hypertension.
Hypertension
January 2025
Department of Nephrology, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Germany (S.A.P., I.Q., D. Arifaj, M.K., D. Argov, L.C.R., J.S.).
Background: Ciliary neurotrophic factor (CNTF), mainly known for its neuroprotective properties, belongs to the IL-6 (interleukin-6) cytokine family. In contrast to IL-6, the effects of CNTF on the vasculature have not been explored. Here, we examined the role of CNTF in AngII (angiotensin II)-induced hypertension.
View Article and Find Full Text PDFPlaying a serious game to increase fertility awareness: perceptions of adolescents, parents and teachers.
Hum Fertil (Camb)
December 2025
Instituto Superior Miguel Torga, Coimbra, Portugal.
Infertility is increasing globally, affecting one in six adults due to factors like delayed childbearing and lifestyle changes. Despite the recognition of the importance of increasing fertility awareness, levels remain low. This study evaluated the perceptions of 'FActs!', a serious game aimed at improving adolescents' fertility awareness.
View Article and Find Full Text PDFImmune response profiling of HERV-W envelope proteins in multiple sclerosis: potential biomarkers for disease progression.
Front Immunol
January 2025
Environmental Factors in Degenerative Diseases Research Group. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.
Introduction: The envelope proteins syncytin-1 and pHERV-W from the Human Endogenous Retroviral family 'W' (HERV-W) have been identified as potential risk factors in multiple sclerosis (MS). This study aims to evaluate both humoral and cell-mediated immune response to antigenic peptides derived from these proteins across different clinical forms and inflammatory phases of MS.
Methods: Indirect enzyme-linked immunosorbent assay (ELISA) was employed to measure immunoglobulin G (IgG) responses to syncytin-1 and pHERV-W peptides in MS patients.
Intimate partnerships during COVID-19 for immigrant women in New York City.
J Marriage Fam
February 2025
Department of Population and Public Health Sciences, University of Southern California, Los Angeles, California, USA.
Objective: This study examines perceptions of changes in intimate relationships among partnered, immigrant women in New York City during the first year of the COVID-19 pandemic. We pay close attention to how structural oppression, particularly related to undocumented immigration status, shaped women's experiences with their intimate partners during a period of social upheaval.
Background: COVID-19 has exacerbated many existing structural inequities and subsequent stressors that have been shown to have an adverse effect on intimate relationships, including increased economic instability and mental health distress.
Older women in the criminal justice system: a brief report from a nominal group.
J Forens Psychiatry Psychol
December 2024
Division of Psychology and Mental Health, School of Health Sciences, University of Manchester, Manchester, UK.
There are increasing numbers of older women in prison in England and Wales. The needs of older women in prison have been under researched and are often unmet. This paper explores staff and expert perspectives on the needs of older women in prison through a nominal group attended by six participants, including a consultant at the UK Health Security Agency; a General Practitioner; a postgraduate student completing a project on older women in prison; an academic researcher with expertise on older women in prison; a National Women's Health, Social Care, and Environment Review Group lead; and a HMMPS Diversity and Inclusion Lead.
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