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VENOUS THROMBOEMBOLISM RISK ASSESSMENT IN HOSPITALISED PATIENTS IN A TERTIARY CARE HOSPITAL IN PAKISTAN.
J Ayub Med Coll Abbottabad
November 2024
Rawalpindi Institute of Cardiology, Rawalpindi-Pakistan.
Article Synopsis
- Venous thromboembolism (VTE) is a major health issue, particularly affecting the elderly, leading to high recurrence rates and increased healthcare costs, prompting the study to assess the impact of a VTE risk assessment tool and thromboprophylaxis in hospitalized patients.
- Conducted in a tertiary hospital in Pakistan, the study evaluated 1,200 adult inpatients, finding that only 15.83% of medical records documented a VTE risk assessment, and thromboprophylaxis was prescribed to just 37.5% of patients.
- The findings highlight that many hospitalized patients are at high risk for VTE, primarily due to old age, yet the implementation of VTE risk assessments and the use of
"Inpatient pharmacological thromboprophylaxis in the antepartum period: an argument for universal thromboprophylaxis".
Am J Obstet Gynecol MFM
November 2024
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, MO (Burd and Zofkie).
Venous thromboembolism (VTE), a largely preventable condition, accounts for almost 15% of maternal mortalities. The physiologic changes of pregnancy, including quantitative changes in coagulation factors and compression of vasculature by the gravid uterus, cause an increase in risk of VTE, including deep vein thromboembolism (DVT), pulmonary embolism, and stroke (CVA). Long term antepartum admission for preeclampsia, preterm prelabor rupture of membranes (PPROM) or other high-risk pregnancy needs present additional risk factors for VTE due to the patient's medical condition and their inpatient status.
View Article and Find Full Text PDFPerioperative Tranexamic Acid Should Be Considered for Total Joint Arthroplasty Patients Receiving Apixaban for Thromboprophylaxis.
Arthroplast Today
December 2024
Department of Orthopaedic Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Article Synopsis
- This study examines whether giving tranexamic acid (TXA) to total joint arthroplasty (TJA) patients receiving apixaban can lower the risk of postoperative bleeding without increasing thromboembolic events.
- Researchers analyzed data from over 118,000 TJA patients and found that those who received both apixaban and TXA had significantly lower rates of bleeding complications and transfusions compared to those who only received apixaban.
- The findings suggest that using TXA in conjunction with apixaban during surgery is beneficial for reducing bleeding risks without raising the chances of serious blood clots or heart problems, making it a recommended practice for surgeons.
Refining the CHA2DS2VASc risk stratification scheme: shall we drop the sex category criterion?
Europace
November 2024
Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, UK.
Aims: The CHA2DS2VASc score is recommended for stroke risk stratification in patients with atrial fibrillation (AF). This score assigns one extra point to female sex based on evidence from the early 2000s, suggesting higher thromboembolic risk in women. This incremental risk of thromboembolism in women has decreased over time between 2007 and 2018, becoming non-significant in recent years.
View Article and Find Full Text PDFDecision Support Intervention and Anticoagulation for Emergency Department Atrial Fibrillation: The O'CAFÉ Stepped-Wedge Cluster Randomized Clinical Trial.
JAMA Netw Open
November 2024
Division of Research, Kaiser Permanente Northern California, Oakland.
Importance: Oral anticoagulation for adults with atrial fibrillation or atrial flutter (AFF) who are at elevated stroke risk reduces the incidence of ischemic stroke but remains underused. Efforts to increase anticoagulation initiation on emergency department (ED) discharge have yielded conflicting results.
Objective: To evaluate the effectiveness of a multipronged intervention supporting anticoagulation initiation for eligible adult ED patients.
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